●
indicate corresponding authors
![2020
Pony P, Rapisarda C, Terradot L, Marza E, Fronzes R. ● (2020) Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for substrate channeling and enzymatic regulation. Nat Commun.11(1):1426.
Coronas-Serna JM, Louche A, Rodriguez-Escudero M, Roussin M, Imbert PRC, Rodriguez-Escudero I, Terradot L, Molina M, Gorvel JP, Cid VJ, Salcedo SP ●. (2020) The TIR-domain containing effectors BtpA and BtpB from Brucella abortus impact NAD metabolism. PLoS Pathog.16(4):e1007979.
Wiegand T ●, Schledorn M, Malar AA, Cadalbert R, Dapp A, Terradot L, Meier BH, Bockmann A. ● (2020) Nucleotide Binding Modes in a Motor Protein Revealed by (31) P- and (1) H-Detected MAS Solid-State NMR Spectroscopy. Chembiochem.;21(3):324-30.
2019
Liu L, Gueguen-Chaignon V, Gonçalves IR, Rascle C, Rigault M, Dellagi A, Loisel E, Poussereau N, Rodrigue A, Terradot L•, Condemine G•. A secreted metal-binding protein protects necrotrophic phytopathogens from reactive oxygen species. Nat Commun. 2019 Oct 24;10(1):4853. doi: 10.1038/s41467-019-12826-x.
Wiegand T, Cadalbert R, Lacabanne D, Timmins J, Terradot L, Böckmann A, Meier BH. The conformational changes coupling ATP hydrolysis and translocation in a bacterial DnaB helicase. Nat Commun. 2019 Jan 3;10(1):31.
2018
Sodolescu A, Dian C, Terradot L, Bouzhir-Sima L, Lestini R, Myllykallio H, Skouloubris S, Liebl U ●. Structural and functional insight into serine hydroxymethyltransferase from Helicobacter pylori. PLoS One. 2018 Dec 14;13(12):e0208850.
Zhao Q, Busch B, Jiménez-Soto LF, Ishikawa-Ankerhold H, Massberg S, Terradot L, Fischer W, Haas R ●. Integrin but not CEACAM receptors are dispensable for Helicobacter pylori CagA translocation. PLoS Pathog. 2018 Oct 26;14(10):e1007359.
Bats SH, Bergé C, Coombs N, Terradot L, Josenhans C ●. Biochemical characterization of the Helicobacter pylori Cag Type 4 Secretion System protein CagN and its interaction partner CagM. Int J Med Microbiol. 2018 Mar 6. pii:S1438-4221(18)30072-9. doi: 10.1016/j.ijmm.2018.02.005.
2017
Koelblen T, Bergé C, Cherrier MV, Brillet K, Jimenez-Soto L, Ballut L, Takagi J, Montserret R, Rousselle P, Fischer W, Haas R, Fronzes R, Terradot L•. Molecular dissection of protein-protein interactions between integrin α5β1 and the Helicobacter pylori Cag Type IV secretion system. FEBS J. 2017 Oct 21. doi: 10.1111/febs.14299. [Epub ahead of print] PubMed PMID: 29055076.
Filomena A, Guenther A, Planatscher H, Topin F, She J, Formichella L, Terradot L, Gerhard M, Joos TO, Meyer H, Schneiderhan-Marra N•. Performance of a Multiplex Serological Helicobacter pylori Assay on a Novel Microfluidic Assay Platform. Proteomes. 2017 Oct 3;5(4). pii: E24. doi: 10.3390/proteomes5040024. PubMed PMID: 28972560.
Imbert PRC, Louche A, Grandjean T, Bigot S, Gagné S, Wood T, Wunderley L, Luizet JB, Terradot L, Garvis S, Filloux A, Guery B, Woodman P, Salcedo SP• (2017) PumA, a novel virulence factor from a Pseudomonas aeruginosa multidrug resistant strain targeting UBAP1 and TLR pathways. EMBO J. 36(13):1869-1887
Wiegand T, Cadalbert R, Gardiennet C, Timmins J, Terradot L•, Bockmann A•, Meier BH• (2017) Solid-state NMR and EPR Spectroscopy of Mn(2+) -Substituted ATP-Fueled Protein Engines. Angew Chem Int Ed Engl 56(12):3369-3373
Bergé C, Terradot L• (2017) Structural insights into Cag protein interactions with host cell partners. Chapter 6 in Molecular Pathogenesis and Signal Transduction by Helicobacter pylori. Current Topics in Microbiology and Immunology.
Wiegand T, Lacabanne D, Keller K, Cadalbert R, Lecoq L, Yulikov M, Terradot L•, Jeschke G, Meier BH• , Bockmann A• (2017) Solid-state NMR and EPR Spectroscopy of Mn2+-Substituted ATP Fueled Protein Engines. Angew Chem Int Ed Engl
2016
Rigard M, Bröms JE, Mosnier A, Hologne M, Martin A, Lindgren L, Punginelli C, Lays C, Walker O, Charbit A, Telouk P, Conlan W, Terradot L ●, Sjöstedt A ●, Henry T ●. (2016) Francisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins
and Harbors a Unique N-terminal Extension Required for Virulence. PLoS Pathog. 12(9):e1005821. doi: 10.1371/journal.ppat.1005821.
Wiegand T, Cadalbert R, Gardiennet C, Timmins J, Terradot L•, Bockmann A•, Meier BH• (2016) Monitoring ssDNA Binding to the DnaB Helicase from Helicobacter pylori by Solid-State NMR Spectroscopy. Angew Chem Int Ed Engl 55: 14164-14168
Wiegand T, Gardiennet C, Cadalbert R, Lacabanne D, Kunert B, Terradot L ●, Böckmann A ●, Meier BH ●. (2016) Variability and conservation of structural domains in divide-and-conquer approaches. J Biomol NMR. 2016 Jun;65(2):79-86.
Gardiennet C, Wiegand T, Bazin A, Cadalbert R, Kunert B, Lacabanne D, Gutsche I, Terradot L ●, Meier BH ●, Böckmann A ● .(2016) Solid-state NMR chemical-shift perturbations indicate domain reorientation of the DnaG primase in the primosome of Helicobacter pylori. J Biomol NMR. 64(3):189-95.
Cheng B., Montmasson M., Terradot L., Rousselle P ● . (2016) Syndecans as Cell Surface Receptors in Cancer Biology. A Focus on their Interaction with PDZ Domain Proteins. Front Pharmacol. 7:10.
Felicori, L, Jameson, KH, Fogg, MJ, Roblin, P, Garcia, T, Ventroux, M, Cherrier, MV, Bazin, A, Noirot, P, Wilkinson, AJ, Molina F ●, Terradot L ●, Noirot-Gros MF ● . (2016) Structural characterization of the replication initiation controller YabA reveals interdomain flexibility. Nucleic Acids Research. 44(1):449-63.
2015
Flayhan A, Bergé C, Baïlo N, Doublet P, Bayliss R and Terradot L ●. (2015) The structure of Legionella pneumophila LegK4 type four secretion system (T4SS) effector reveals a novel dimeric eukaryotic-like kinase. Scientific Reports. 5:14602. doi: 10.1038/srep14602.
Bazin A, Cherrier MV, Gutsche I, Timmins J, Terradot L ●. (2015) Structure and primase-mediated activation of a bacterial dodecameric replicative helicase. Nucleic Acids Res.43(17):8564-76.
Wiegand T, Gardiennet C, Ravotti F, Bazin A, Kunert B, Lacabanne D, Cadalbert R, Güntert P, Terradot L ●, Böckmann A ●, Meier BH ●. (2015) Solid-state NMR sequential assignments of the N-terminal domain of HpDnaB helicase. Biomol NMR Assign.
2014
Felix C, Kaplan Türköz B, Ranaldi S, Koelblen T, Terradot L, O'Callaghan D ●, Vergunst AC ●. (2014) The Brucella TIR domain containing proteins BtpA and BtpB have a structural WxxxE motif important for protection against microtubule depolymerisation. Cell Commun Signal. 2014 Oct 12;12:53
2013
Kaplan-Türköz B, Koelblen T, Felix C, Candusso MP, O'Callaghan D, Vergunst AC, Terradot L ● (2013) Structure of the Toll/interleukin 1 receptor (TIR) domain of the immunosuppressive Brucella effector BtpA/Btp1/TcpB.FEBS Letter 587(21):3412-6.
Kaplan-Türköz B and Terradot L●. Structure and mode of injection of the oncoprotein CagA of Helicobacter pylori. Médecine/Sciences 29, 25-27.
2012
Stelter M, Gutsche I, Kapp U, Bazin A, Bajic G, Goret G, Jamin M, Timmins J, and Terradot L.● (2012) Architecture of a dodecameric bacterial replicative helicase. Structure 20, 554-64.
Kaplan-Turkoz B, Jimenez-Soto LF, Dian C, Ertl C, Remaut H, Louche A, Tosi T, Haas R ●, and Terradot L.● (2012) Structural insights into Helicobacter pylori oncoprotein CagA interaction with beta1 integrin. Proc Natl Acad Sci U S A 109, 14640-5.
Gardiennet, C, Schutz A K, Hunkeler A, Kunert B, Terradot L, Bockmann A ●, and Meier BH ● (2012) A sedimented sample of a 59 kDa dodecameric helicase yields high-resolution solid-state NMR spectra. Angew Chem Int Ed Engl 51, 7855-8.
2011
Terradot, L●. and Noirot-Gros, M.F. ● (2011) Bacterial protein interaction networks: puzzle stones from solved complexes structures add to a clearer picture. Integrative Biology. 3, 645-52.
Cioci, G., Terradot, L., Dian, C., Mueller-Dieckmann, C., Leonard, G. ● (2011) Crystal structure of HP0721, a novel secreted protein from Helicobacter pylori. Proteins. doi: 10.1002/prot.22988. [Epub ahead of print].
Zawilak-Pawlik, A. ●, Donczew, R., Szafranski, S., Mackiewicz, P., Terradot, L., and Zakrzewska-Czerwinska, L. ● (2011) DiaA/HobA and DnaA – a pair of proteins which co-evolved to cooperate during bacterial orisome assembly. J. Mol. Biol. 408(2):238-51.
Terradot, L. ● and Waksman, G. ● (2011) Architecture of the Helicobacter pylori Cag- Type IV secretion system. FEBS Journal. 278 :1213–22.
Dian, C., Vitale, S., Leonard, G.A., Bahlawane, C., Fauquant, C., Leduc, D., Muller, C., de Reuse, H., Michaud-Soret, I. ●, Terradot, L. ● (2011) The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites. Mol. Microbiol. 79(5):1260-75.
2010
Terradot L. ● and Zawilak-Pawlik A. (2010) Structural insight into Helicobacter pylori DNA replication initiation. Gut Microbes, 1(5); 1-5.
Bahlawane, C., Dian, C., Muller, C., Round, A., Fauquant, C., Schauer,K., de Reuse, H., Terradot, L. ● and Michaud-Soret, I. ● (2010) Structural and mechanistic insights into Helicobacter pylori NikR activation. Nucleic Acid Research, 38(9):3106-18.
2009
Jiménez-Soto, L.F., Sewald, X., Kutter, S., Ertl, C., Weiss, E., Rohde, M., Pirch, T., Jung, K., Terradot, L., Fischer, W. and Haas, R. (2009) Helicobacter pylori Type IV Secretion Apparatus Exploits β1 Integrin in a Novel RGD-Independent Manner. PLoS Pathogens Dec 5(12): e1000684.doi:10.1371.
Natrajan, G., Noirot-Gros, M.F., Zawilak-Pawilk, A., Kapp, U., and Terradot, L●. (2009) Structure of a DnaA/HobA complex from Helicobacter pylori: insights into regulation of DNA replication in Gram-negative bacteria. Proc Natl Acad Sci U S A. 106, 21115-20.
Tosi, T., Cioci, G., Jouravleva, K., Dian, C. and Terradot, L●. (2009) Crystal structures of the Tumor Necrosis Factor α inducing protein (Tipα): a novel Helicobacter pylori toxin involved in gastric carcinogenesis. FEBS Letter 583, 1581-5.
Angelini, A., Tosi, T., Mas, P., Acajjaoui, S., Zanotti, G., Terradot, L.●, and Hart D.J*. (2009) Expression of Helicobacter pylori CagA soluble fragments by library-based construct screening. FEBS Journal, 276, 816-24.
2008
Angelini, A., Cendron, L., Goncalves, S., Zanotti, G. & Terradot, L●. (2008) Structural and enzymatic characterisation of HP0496, a YbgC thioesterase from Helicobacter pylori. Proteins, 72, 1212-21.
Loguercio, S., Dian, C., Flagiello, A., Scannella, A., Pucci, P., Terradot, L●., and Zagari, A●. (2008) In HspA from Helicobacter pylori vicinal disulfide bridges are a key determinant of domain B structure. FEBS letter, 582, 3537–41.
Terradot L●. and Giblot Ducray-Bourdin D. (2008). Les interactions virus-pucerons et leurs conséquences épidémiologiques. In ‘Les virus des Solanacées’. Inra Editions.
2007
Hare, S., Fisher, W., Williams, R., Terradot, L., Bayliss, R., Haas, R.& Waksman, G. ● (2007). Identification, structure and mode of action of a new regulator of the Helicobacter pylori HP0525 ATPase. EMBO J. 26:4926-34.
Natrajan, G., Hall, D. R., Thompson, A. C., Gutsche, I. & Terradot, L●. (2007). Structural similarity between the DnaA-binding proteins HobA (HP1230) from Helicobacter pylori and DiaA from Escherichia coli. Mol Microbiol 65, 995-1005.
2006
Fauquant, C., Diederix, R. E. M., Rodrigue, A., Dian, C., Kapp, U., Terradot, L., Mandrand-Berthelot, M. A. & Michaud-Soret, I. ● (2006). pH dependent Ni(II) binding and aggregation of Escherichia coli and Helicobacter pylori NikR. Biochimie 88(11), 1693-705.
Dian, C., Schauer, K., Kapp, U., McSweeney, S. M., Labigne, A. & Terradot, L●. (2006). Structural basis of the nickel response in Helicobacter pylori: crystal structures of HpNikR in Apo and nickel-bound states. J Mol Biol 361, 715-30.
2005
Terradot, L., Bayliss, R., Oomen, C., Leonard, G. A., Baron, C. & Waksman, G. ● (2005). Structures of two core subunits of the bacterial type IV secretion system, VirB8 from Brucella suis and ComB10 from Helicobacter pylori. Proc Natl Acad Sci U S A 102, 4596-601.
2004
Terradot, L., Durnell, N., Li, M., Li, M., Ory, J., Labigne, A., Legrain, P., Colland, F. & Waksman, G. ● (2004). Biochemical characterization of protein complexes from the Helicobacter pylori protein interaction map: strategies for complex formation and evidence for novel interactions within type IV secretion systems. Mol Cell Proteomics 3, 809-19.
Leiros, H. K., Kozielski-Stuhrmann, S., Kapp, U., Terradot, L., Leonard, G. A. & McSweeney, S. M. ● (2004). Structural basis of 5-nitroimidazole antibiotic resistance: the crystal structure of NimA from Deinococcus radiodurans. J Biol Chem 279, 55840-9.
Terradot L●. Virus: architecture and composition. Chapter I, In Virus diseases of Poaceae (H. Lapierre and R. Signoret, Eds) 2004.
1996-2001
Terradot, L●., Souchet, M., Tran, V. & Giblot Ducray-Bourdin, D. (2001). Analysis of a three-dimensional structure of Potato leafroll virus coat protein obtained by homology modeling. Virology 286, 72-82.
Rouze-Jouan, J., Terradot, L., Pasquer, F., Tanguy, S. & Giblot Ducray-Bourdin, D. ● (2001). The passage of Potato leafroll virus through Myzus persicae gut membrane regulates transmission efficiency. J Gen Virol 82, 17-23.
Terradot, L., Simon, J. C., Leterme, N., Bourdin, D., Wilson, A. C. C., Gauthier, J. P. & Robert, Y. ● (1999). Molecular characterization of clones of the Myzus persicae complex (Hemiptera: Aphididae) differing in their ability to transmit the potato leafroll luteovirus (PLRV). Bulletin of Entomological Research 89, 355-363.
Assagui R., Lorenzetti F., Terradot L., Regnault-Roger C., Malo N., Wiriyachitra P., Sanchez-Vindas P.E., San Roman L , Isman M.B., Durst T. and J.T Arnason. ● (1997). Efficacy of botanicals from the Meliaceae and Piperaceae. In : Phytochemicals for Pest Control, J.A.C.S. symposiums series 658, 39-48.](Publications_files/shapeimage_3.png)
